NHGDoc is a clinical decision support system for general practitioners (GP’s), nurse practitioners and GP’s assistants available in the GP Information System. The system compares information from the EHR with the recommendations in Dutch guidelines. When a deviation from the guidelines is spotted in the EHR, NHGDoc generates an alert. With NHGDoc users have all-time access to patient tailored guideline recommendations at the point-of-care that allows them to make faster and smarter decisions, avoid mistakes and find blind spots. Already 2,500 GP practices in the Netherlands are connected to NHGDoc.